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DTaP vaccine can prevent diphtheria, tetanus, and pertussis.
Diphtheria and pertussis spread from person to person. Tetanus enters the body through cuts or wounds.
DIPHTHERIA (D) can lead to difficulty breathing, heart failure, paralysis, or death.
TETANUS (T) causes painful stiffening of the muscles. Tetanus can lead to serious health problems, including being unable to open the mouth, having trouble swallowing and breathing, or death.
PERTUSSIS (aP), also known as “whooping cough,” can cause uncontrollable, violent coughing which makes it hard to breathe, eat, or drink. Pertussis can be extremely serious in babies and young children, causing pneumonia, convulsions, brain damage, or death. In teens and adults, it can cause weight loss, loss of bladder control, passing out, and rib fractures from severe coughing.
DTaP is only for children younger than 7 years old. Different vaccines against tetanus, diphtheria, and pertussis (Tdap and Td) are available for older children, adolescents, and adults.
It is recommended that children receive 5 doses of DTaP, usually at the following ages:
2 months
4 months
6 months
15–18 months
4–6 years
DTaP may be given as a stand-alone vaccine, or as part of a combination vaccine (a type of vaccine that combines more than one vaccine together into one shot).
DTaP may be given at the same time as other vaccines.
Tell your vaccine provider if the person getting the vaccine:
Has had an allergic reaction after a previous dose of any vaccine that protects against tetanus, diphtheria, or pertussis, or has any severe, life-threatening allergies.
Has had a coma, decreased level of consciousness, or prolonged seizures within 7 days after a previous dose of any pertussis vaccine (DTP or DTaP).
Has seizures or another nervous system problem.
Has ever had Guillain-Barré Syndrome (also called GBS).
Has had severe pain or swelling after a previous dose of any vaccine that protects against tetanus or diphtheria.
In some cases, your child’s health care provider may decide to postpone DTaP vaccination to a future visit.
Children with minor illnesses, such as a cold, may be vaccinated. Children who are moderately or severely ill should usually wait until they recover before getting DTaP.
Your child’s health care provider can give you more information.
Soreness or swelling where the shot was given, fever, fussiness, feeling tired, loss of appetite, and vomiting sometimes happen after DTaP vaccination.
More serious reactions, such as seizures, non-stop crying for 3 hours or more, or high fever (over 105°F) after DTaP vaccination happen much less often. Rarely, the vaccine is followed by swelling of the entire arm or leg, especially in older children when they receive their fourth or fifth dose.
Very rarely, long-term seizures, coma, lowered consciousness, or permanent brain damage may happen after DTaP vaccination.
As with any medicine, there is a very remote chance of a vaccine causing a severe allergic reaction, other serious injury, or death.
An allergic reaction could occur after the vaccinated person leaves the clinic. If you see signs of a severe allergic reaction (hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness), call 9-1-1 and get the person to the nearest hospital.
For other signs that concern you, call your health care provider.
Adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your health care provider will usually file this report, or you can do it yourself. Visit the VAERS website at
The National Vaccine Injury Compensation Program (VICP) is a federal program that was created to compensate people who may have been injured by certain vaccines. Visit the VICP website at
Ask your health care provider.
Call your local or state health department.
Contact the Centers for Disease Control and Prevention (CDC):
Call 1-800-232-4636 (1-800-CDC-INFO) or
Visit CDC’s website at
Vaccine Information Statement (inTerim)
DTaP (Diphtheria, Tetanus) Vaccine
04/01/2020
42 U.S.C § 300aa-26
Department of Health and Human Services
Centers for Disease and Prevention
Many Vaccine Information Statements are available in Spanish and other languages. See
Hojas de información sobre vacunas están disponibles en español y en muchos otros idiomas. Visite
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